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How Much of our Behaviour is Pre-determined by our Underlying Biology?

“As Stefánsson found with crosswords, it seems our genes influence our natural inclinations towards doing certain activities. What truly dictates whether we have any aptitude for them are factors such as whether we receive tutoring and other opportunities at an early age, and our own willingness to practice, improve and persist. The environment we find ourselves in plays a huge role in determining whether we act on our genetic inclinations or not. Stefánsson says that people who have genetic variants in their brain which make them struggle with inhibition are going to be more likely to overeat if they work next to fast food outlets, and struggle to quit if they begin smoking. But at the same time, there is evidence that having a  stable family life ,  stable romantic relationships and friendships , or even  exercising regularly  can help them live a productive life.” Genetics and life choices
In my reading list:  Guns, Germs and Steel  (Jared Diamond, 2010) The book sounds as a confirmation of the following premises. "The premises from which we begin are not arbitrary ones, not dogmas, but real premises from which abstraction can only be made in the imagination. They are the real individuals, their activity and the material conditions under which they live, both those which they find already existing and those produced by their activity. These premises can thus be verified in a purely empirical way. The first premise of all human history is, of course, the existence of living human individuals. Thus the first fact to be established is the physical organisation of these individuals and their consequent relation to the rest of nature. Of course, we cannot here go either into the actual physical nature of man, or into the natural conditions in which man finds himself – geological, hydrographical, climatic and so on. The writing of history must always set out